Digital health technologies are becoming increasingly pervasive. These tools increase opportunities to measure physiology and behavior in the wild (i.e., outside the laboratory). Evolving sensing technologies and data analytic solutions could transform sensor data into clinically actionable information. The IEEE-EMBS International Conference on Body Sensor Networks – Computational Medicine: Expanding Health through Sensing and AI (BSN 2025) will address digital health research and offer participants a unique forum to discuss the key issues and innovative solutions for sensor and systems development, data analytics and modeling, data management and interpretation, and communications.